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Killer artificiale cellule presentanti l'antigene (KaAPC) per una efficiente<em> In Vitro</em> L'esaurimento delle Umana antigene-specifiche cellule T
JoVE Journal
Immunology and Infection
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JoVE Journal Immunology and Infection
Killer Artificial Antigen Presenting Cells (KaAPC) for Efficient In Vitro Depletion of Human Antigen-specific T Cells
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Killer artificiale cellule presentanti l'antigene (KaAPC) per una efficiente<em> In Vitro</em> L'esaurimento delle Umana antigene-specifiche cellule T

italiano

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9,564 Views

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08:12 min

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August 11, 2014

DOI:

10.3791/51859-v

DOI:
10.3791/51859-v

•

08:12 min
August 11, 2014

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7 Views
, , ,
1Department of Pathology, Institute of Cell Engineering,Johns Hopkins University, 2Department of Internal Medicine I,University of Regensburg, 3Department of Rheumatology,Asklepios Medical Center

Summary

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Orientamenti sono presentati per la generazione di antigene artificiale assassino cellule presentanti, KaAPC, uno strumento efficace per deplezione in vitro di cellule T antigene-specifiche umani e una soluzione alternativa per immunoterapia cellulare per il trattamento delle malattie autoimmuni mediate da cellule T in un antigene modo specifico senza compromettere il sistema immunitario rimanente.

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Cite this Article

Schütz, C., Fleck, M., Schneck, J. P., Oelke, M. Killer Artificial Antigen Presenting Cells (KaAPC) for Efficient In Vitro Depletion of Human Antigen-specific T Cells. J. Vis. Exp. (90), e51859, doi:10.3791/51859 (2014).

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