Journal
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评估在功能性能<em> MDX</em>小鼠模型
JoVE Journal
Behavior
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JoVE Journal Behavior
Assessing Functional Performance in the Mdx Mouse Model
DOI:

10:32 min

March 27, 2014

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Chapters

  • 00:05Title
  • 02:39Hanging Tests: Two Limbs
  • 04:07Hanging Tests: Four Limbs
  • 05:00Rotarod Running
  • 06:16Treadmill Exercise
  • 06:50Results: Functional Performance of Mdx and Wild Type Mice
  • 09:49Conclusion
  • 10:31Forelimb Grip Strength Test

Summary

Automatic Translation

在对神经肌肉疾病的临床试验的主要终点是普遍改善肌肉功能。因此,评估潜在的治疗化合物对肌肉性能在小鼠模型中的临床前的效果是非常重要的。我们在这里介绍几种功能测试,以解决这一问题。

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