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Assessing Functional Performance in the Mdx Mouse Model
Kapitel
- 00:05Titel
- 02:39Hanging Tests: Two Limbs
- 04:07Hanging Tests: Four Limbs
- 05:00Rotarod Running
- 06:16Treadmill Exercise
- 06:50Results: Functional Performance of Mdx and Wild Type Mice
- 09:49Conclusion
- 10:31Forelimb Grip Strength Test
The primary outcome measure in clinical trials for neuromuscular disorders is generally improved muscle function. Therefore, assessing the effect of potential therapeutic compounds on muscle performance pre clinically in mouse models is of great importance. We here describe several functional tests to address this.
