Chen, H., Perez, J. N., Constantopoulos, E., McKee, L., Regan, J., Hoyer, P. B., Brooks, H. L., Konhilas, J. A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice. J. Vis. Exp. (86), e51083, doi:10.3791/51083 (2014).