Two exercise paradigms were tested on a newly developed chemically induced menopausal mouse model to examine the impact of menopause on exercise capacity and cardiac adaption to exercise.
Chen, H., Perez, J. N., Constantopoulos, E., McKee, L., Regan, J., Hoyer, P. B., Brooks, H. L., Konhilas, J. A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice. J. Vis. Exp. (86), e51083, doi:10.3791/51083 (2014).