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Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants
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Medicine
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JoVE Journal Medicine
Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants

Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants

English

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19,812 Views

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11:39 min

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March 14, 2013

DOI:

10.3791/4379-v

DOI:
10.3791/4379-v

•

11:39 min
March 14, 2013

•

3 Views
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1Athinoula A. Martinos Center for Biomedical Imaging,Massachusetts General Hospital, Harvard Medical School, 2Lab. PALM,Université de Caen Basse-Normandie, 3Fetal-Neonatal Neuroimaging and Developmental Science Center,Boston Children’s Hospital, Harvard Medical School, 4ISS, INC.

Summary

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We combined frequency-domain near-infrared spectroscopy measures of cerebral hemoglobin oxygenation with diffuse correlation spectroscopy measures of cerebral blood flow index to estimate an index of oxygen metabolism. We tested the utility of this measure as a bedside screening tool to evaluate the health and development of the newborn brain.

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Lin, P., Roche-Labarbe, N., Dehaes, M., Carp, S., Fenoglio, A., Barbieri, B., Hagan, K., Grant, P. E., Franceschini, M. A. Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants. J. Vis. Exp. (73), e4379, doi:10.3791/4379 (2013).

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