We combined frequency-domain near-infrared spectroscopy measures of cerebral hemoglobin oxygenation with diffuse correlation spectroscopy measures of cerebral blood flow index to estimate an index of oxygen metabolism. We tested the utility of this measure as a bedside screening tool to evaluate the health and development of the newborn brain.
Lin, P., Roche-Labarbe, N., Dehaes, M., Carp, S., Fenoglio, A., Barbieri, B., Hagan, K., Grant, P. E., Franceschini, M. A. Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants. J. Vis. Exp. (73), e4379, doi:10.3791/4379 (2013).