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Preparação e Uso de Samário diiodeto (SMI<sub> 2</sub>) Em Organic Synthesis: The Role mecanístico de HMPA e (II) de Ni Sais na Reacção Barbier Samário
JoVE Journal
Chemistry
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JoVE Journal Chemistry
Preparation and Use of Samarium Diiodide (SmI2) in Organic Synthesis: The Mechanistic Role of HMPA and Ni(II) Salts in the Samarium Barbier Reaction

Preparação e Uso de Samário diiodeto (SMI<sub> 2</sub>) Em Organic Synthesis: The Role mecanístico de HMPA e (II) de Ni Sais na Reacção Barbier Samário

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32,249 Views

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12:22 min

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February 04, 2013

DOI:

10.3791/4323-v

DOI:
10.3791/4323-v

•

12:22 min
February 04, 2013

•

15 Views
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1Department of Chemistry,Lehigh University

Summary

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Um procedimento simples para a preparação de samário diiodeto (SMI<sub> 2</sub>) Em THF é descrito. O papel dos dois aditivos principais a saber hexametilfosforamida (HMPA) e Ni (acac)<sub> 2</sub> Sm em reacções mediadas é demonstrada no Sm-Barbier reacção.

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Sadasivam, D. V., Choquette, K. A., Flowers II, R. A. Preparation and Use of Samarium Diiodide (SmI2) in Organic Synthesis: The Mechanistic Role of HMPA and Ni(II) Salts in the Samarium Barbier Reaction. J. Vis. Exp. (72), e4323, doi:10.3791/4323 (2013).

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