Journal
/
Neuroscience
/
The Mouse Forced Swim Test
JoVE Journal
Neuroscience
Author Produced
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Neuroscience
The Mouse Forced Swim Test

The Mouse Forced Swim Test

English

Automatically Generated

102,649 Views

•

06:19 min

•

January 29, 2012

DOI:

10.3791/3638-v

DOI:
10.3791/3638-v

•

06:19 min
January 29, 2012

•

80 Views
, , , , ,
1Department of Psychiatry,University of Maryland School of Medicine, 2Tulane University School of Medicine, 3Department of Pharmacology and Experimental Therapeutics,University of Maryland School of Medicine, 4The Program in Neuroscience,University of Maryland

Summary

Automatically generated

The forced swim test is validated as an experimental approach to assess potential antidepressant efficacy in rodents. Experimental animals are placed in a tank of water and escape-related mobility behavior is quantified. The common procedures for the mouse version of this test are described.

Explore More Videos

Forced Swim TestRodent Behavioral TestAntidepressant DrugsAntidepressant EfficacyNew CompoundsDepressive-like StatesInescapable Transparent TankWaterEscape-related Mobility BehaviorSpecialized EquipmentProcedural DetailsUnwarranted StressInterpretation Of ResultsBehaviors Assessment

Read Article

Cite this Article

Can, A., Dao, D. T., Arad, M., Terrillion, C. E., Piantadosi, S. C., Gould, T. D. The Mouse Forced Swim Test. J. Vis. Exp. (59), e3638, doi:10.3791/3638 (2012).

Download .ris file

Copy

Share Video

.

Copy