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The Mouse Forced Swim Test
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Journal JoVE Neurosciences
The Mouse Forced Swim Test

The Mouse Forced Swim Test

102,649 Views

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06:19 min

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January 29, 2012

DOI:

10.3791/3638-v

DOI:
10.3791/3638-v

•

06:19 min
January 29, 2012

•

80 Views
, , , , ,
1Department of Psychiatry,University of Maryland School of Medicine, 2Tulane University School of Medicine, 3Department of Pharmacology and Experimental Therapeutics,University of Maryland School of Medicine, 4The Program in Neuroscience,University of Maryland

Summary

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The forced swim test is validated as an experimental approach to assess potential antidepressant efficacy in rodents. Experimental animals are placed in a tank of water and escape-related mobility behavior is quantified. The common procedures for the mouse version of this test are described.

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Can, A., Dao, D. T., Arad, M., Terrillion, C. E., Piantadosi, S. C., Gould, T. D. The Mouse Forced Swim Test. J. Vis. Exp. (59), e3638, doi:10.3791/3638 (2012).

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