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意識、無拘束マウスにおける高インスリン血症、正常血糖クランプ
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November 16, 2011
DOI:
1Diabetes and Obesity Research Center,Sanford-Burnham Medical Research Institute at Lake Nona, 2Department of Molecular Physiology and Biophysics,Vanderbilt University School of Medicine, 3Vanderbilt Mouse Metabolic Phenotyping Center,Vanderbilt University School of Medicine, 4Department of Pediatrics and Cellular and Integrative Physiology,Indiana University School of Medicine
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Hyperinsulinemic-euglycemic ClampsInsulin ActionType 2 DiabetesInsulin InfusionGlucose InfusionGlucose Infusion Rate (GIR)Whole-body Insulin ActionIsotopic 2[14C]deoxyglucose[3-3H]glucoseEndogenous Glucose Appearance (endoRa)Hepatic Glucose ProductionWhole-body Glucose Disappearance (Rd)Genetic Mouse Models Of Metabolic DiseaseDiabetes ResearchInsulin Clamp Performance
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Ayala, J. E., Bracy, D. P., Malabanan, C., James, F. D., Ansari, T., Fueger, P. T., McGuinness, O. P., Wasserman, D. H. Hyperinsulinemic-euglycemic Clamps in Conscious, Unrestrained Mice. J. Vis. Exp. (57), e3188, doi:10.3791/3188 (2011).
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