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Transplantation chirurgicale de cellules souches neurales de souris dans la moelle épinière des souris infectées avec le virus de l'hépatite murine neurotrope
JoVE Journal
Neuroscience
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JoVE Journal Neuroscience
Surgical Transplantation of Mouse Neural Stem Cells into the Spinal Cords of Mice Infected with Neurotropic Mouse Hepatitis Virus
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Transplantation chirurgicale de cellules souches neurales de souris dans la moelle épinière des souris infectées avec le virus de l'hépatite murine neurotrope

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23,001 Views

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08:33 min

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July 10, 2011

DOI:

10.3791/2834-v

DOI:
10.3791/2834-v

•

08:33 min
July 10, 2011

•

4 Views
, , , ,
1Department of Molecular Biology and Biochemistry,University of California, Irvine, 2Sue and Bill Gross Stem Cell Center,University of California, Irvine, 3Institute for Immunology,University of California, Irvine

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Surgical TransplantationMouse Neural Stem CellsSpinal CordsMice InfectedNeurotropic Mouse Hepatitis VirusJHM StrainDemyelinating DiseaseMultiple SclerosisTransplantation Of NSCsRemyelinationClinical OutcomeCell Replacement TherapiesChronic Neurologic DiseasesIn Vivo ModelsEngrafted CellsAdapted MethodI) Preparation Of NSCsIi) Pre-operative Care Of MiceIii) Exposure Of The Spinal Cord Via LaminectomyIv) Stereotactic Injection Of NSCsIv) Post-operative Care

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Carbajal, K. S., Weinger, J. G., Whitman, L. M., Schaumburg, C. S., Lane, T. E. Surgical Transplantation of Mouse Neural Stem Cells into the Spinal Cords of Mice Infected with Neurotropic Mouse Hepatitis Virus. J. Vis. Exp. (53), e2834, doi:10.3791/2834 (2011).

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