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Haute-efficacité de la transduction des cellules cancéreuses du foie par recombinants sérotype virus adéno-associé 3 Vecteurs
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Medicine
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JoVE Journal Medicine
High-Efficiency Transduction of Liver Cancer Cells by Recombinant Adeno-Associated Virus Serotype 3 Vectors
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Haute-efficacité de la transduction des cellules cancéreuses du foie par recombinants sérotype virus adéno-associé 3 Vecteurs

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12,987 Views

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19:02 min

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March 22, 2011

DOI:

10.3791/2538-v

DOI:
10.3791/2538-v

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19:02 min
March 22, 2011

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3 Views
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1Department of Pediatrics, Division of Cellular and Molecular Therapy,University of Florida

Summary

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Dans cet article, nous décrivons l'identification du virus adéno-associé de sérotype 3 (AAV3) comme le vecteur le plus efficace pour cibler les cellules humaines de cancer du foie.

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Recombinant Adeno-associated Virus Serotype 3 VectorsLiver Cancer CellsGene TherapyAAV2AAV SerotypesHuman Liver CancerHepatoblastomaHepatocellular CarcinomaCellular Co-receptorHigh-efficiency TransductionReporter GenePotential Gene Therapy

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Cite this Article

Ling, C., Lu, Y., Cheng, B., McGoogan, K. E., Gee, S. W., Ma, W., Li, B., Aslanidi, G. V., Srivastava, A. High-Efficiency Transduction of Liver Cancer Cells by Recombinant Adeno-Associated Virus Serotype 3 Vectors. J. Vis. Exp. (49), e2538, doi:10.3791/2538 (2011).

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