In this article, we describe the identification of the adeno-associated virus serotype 3 (AAV3) as the most efficient vector for targeting human liver cancer cells.
Ling, C., Lu, Y., Cheng, B., McGoogan, K. E., Gee, S. W., Ma, W., Li, B., Aslanidi, G. V., Srivastava, A. High-Efficiency Transduction of Liver Cancer Cells by Recombinant Adeno-Associated Virus Serotype 3 Vectors. J. Vis. Exp. (49), e2538, doi:10.3791/2538 (2011).