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浆液性卵巢癌原位模型在免疫小鼠，为在体内肿瘤显像和肿瘤免疫反应的监测
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Immunology and Infection
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JoVE Journal Immunology and Infection
An Orthotopic Model of Serous Ovarian Cancer in Immunocompetent Mice for in vivo Tumor Imaging and Monitoring of Tumor Immune Responses
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浆液性卵巢癌原位模型在免疫小鼠，为在体内肿瘤显像和肿瘤免疫反应的监测

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10:35 min

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November 28, 2010

DOI:

10.3791/2146-v

DOI:
10.3791/2146-v

•

10:35 min
November 28, 2010

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1Penn Ovarian Cancer Research Center, Center for Research on Reproduction and Womans Health, Department of Obstetrics and Gynecology,University of Pennsylvania-School of Medicine, 2Women’s Cancer Program,Fox Chase Cancer Center

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Orthotopic ModelSerous Ovarian CancerImmunocompetent MiceIn Vivo Tumor ImagingTumor Immune ResponsesTg-MISIIR-TAg Transgenic Mouse ModelSV40 Transforming RegionMullerian Inhibitory Substance Type II Receptor (MISIIR) Gene PromoterSyngeneic Allograft RecipientsPreclinical StudiesTumor Microenvironment

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Nunez-Cruz, S., Connolly, D. C., Scholler, N. An Orthotopic Model of Serous Ovarian Cancer in Immunocompetent Mice for in vivo Tumor Imaging and Monitoring of Tumor Immune Responses. J. Vis. Exp. (45), e2146, doi:10.3791/2146 (2010).

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