Journal
/
Biochemistry
/
In Silico Structural Analysis of Protein Carbonylation by Lipid Derivatives
/
Computational Design and Energy Optimization of Modified Amino Acids Reacting with Lipid Peroxidation Aldehydes
JoVE Journal
Biochemistry
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Biochemistry
Computational Design and Energy Optimization of Modified Amino Acids Reacting with Lipid Peroxidation Aldehydes

Computational Design and Energy Optimization of Modified Amino Acids Reacting with Lipid Peroxidation Aldehydes

In Silico Structural Analysis of Protein Carbonylation by Lipid Derivatives

DOI:
10.3791/201707-v

•

01:29 min

•

April 26, 2024

•

, , , , ,
1Analytical Chemistry and Biomedicine Group, Exact and Natural Sciences Faculty,University of Cartagena, 2Analytical Chemistry and Biomedicine Group, Pharmaceutical Sciences Faculty,University of Cartagena, 3Pharmacology and Therapeutics Research Group,University of Cartagena

Tags

Protein CarbonylationReactive Carbonyl SpeciesLipid Peroxidation4-hydroxy-2-nonenal (HNE)4-hydroxy-2-hexenal (HHE)4-Oxo-2-nonenal (ONE)Malondialdehyde (MDA)Molecular Dynamics SimulationsStructural ChangesAmino Acid ModificationThioredoxinBovine Serum AlbuminZu-5-ankyrin Domain

Embed

ADD TO PLAYLIST

Usage Statistics

Related Videos

Author Spotlight: In Silico Creation and Impact of Carbonylated Amino Acids on Protein Structure and Function

Computational Design and Energy Optimization of Modified Amino Acids Reacting with Lipid Peroxidation Aldehydes

Parameterization of Modified Amino Acid Residues into the Thioredoxin Protein Structure

Read Article