Journal
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Bioquímica
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In Silico Structural Analysis of Protein Carbonylation by Lipid Derivatives
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Computational Design and Energy Optimization of Modified Amino Acids Reacting with Lipid Peroxidation Aldehydes
JoVE Journal
Bioquímica
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JoVE Journal Bioquímica
Computational Design and Energy Optimization of Modified Amino Acids Reacting with Lipid Peroxidation Aldehydes

Computational Design and Energy Optimization of Modified Amino Acids Reacting with Lipid Peroxidation Aldehydes

In Silico Structural Analysis of Protein Carbonylation by Lipid Derivatives

DOI:
10.3791/201707-v

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01:29 min

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April 26, 2024

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, , , , ,
1Analytical Chemistry and Biomedicine Group, Exact and Natural Sciences Faculty,University of Cartagena, 2Analytical Chemistry and Biomedicine Group, Pharmaceutical Sciences Faculty,University of Cartagena, 3Pharmacology and Therapeutics Research Group,University of Cartagena

Tags

Protein CarbonylationReactive Carbonyl SpeciesLipid Peroxidation4-hydroxy-2-nonenal (HNE)4-hydroxy-2-hexenal (HHE)4-Oxo-2-nonenal (ONE)Malondialdehyde (MDA)Molecular Dynamics SimulationsStructural ChangesAmino Acid ModificationThioredoxinBovine Serum AlbuminZu-5-ankyrin Domain

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