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Combinando QD-FRET e microfluidica per il monitoraggio Nanocomplex DNA di auto-assemblaggio in tempo reale
JoVE Journal
Biology
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JoVE Journal Biology
Combining QD-FRET and Microfluidics to Monitor DNA Nanocomplex Self-Assembly in Real-Time
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Combinando QD-FRET e microfluidica per il monitoraggio Nanocomplex DNA di auto-assemblaggio in tempo reale

italiano

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10,895 Views

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14:36 min

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August 26, 2009

DOI:

10.3791/1432-v

DOI:
10.3791/1432-v

•

14:36 min
August 26, 2009

•

1 Views
, , ,
1Mechanical Engineering,Johns Hopkins University, 2Biomedical Engineering,Duke University, 3Biomedical Engineering,Johns Hopkins University

Summary

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Vi presentiamo un nuovo e potente integrazione di nanofotonica (QD-FRET) e microfluidica per studiare la formazione di polyplexes polielettrolita, che si prevede di fornire un migliore controllo e la sintesi di polyplexes uniforme e personalizzabili per i futuri nucleici terapie a base di acido.

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Ho, Y., Chen, H. H., Leong, K. W., Wang, T. Combining QD-FRET and Microfluidics to Monitor DNA Nanocomplex Self-Assembly in Real-Time. J. Vis. Exp. (30), e1432, doi:10.3791/1432 (2009).

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