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April 29, 2009
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Mammary tumor cells expressing luciferase are implanted subcutaneously in mice and visualized using optical imaging to monitor tumor growth and development non-invasively in a longitudinal study.
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In Vivo Bioluminescent ImagingMammary TumorsIVIS Spectrum4T1 Mouse Mammary Tumor CellsXenograft Tumor ModelPre-clinical EvaluationAntitumor CompoundsFirefly Luciferase GeneLuciferin InjectionOptical Imaging SystemPhoton FluxAbsolute QuantitationLongitudinal StudiesTumor Growth MonitoringEarly Events In Tumor DevelopmentBioluminescent Signal ReductionTumor Cell DeathHypoxiaDrug Treatment
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Lim, E., Modi, K. D., Kim, J. In vivo Bioluminescent Imaging of Mammary Tumors Using IVIS Spectrum. J. Vis. Exp. (26), e1210, doi:10.3791/1210 (2009).
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