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In Vivo Real-Time Study of Drug Effects on Carotid Blood Flow in the Ovine Fetus
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In Vivo Real-Time Study of Drug Effects on Carotid Blood Flow in the Ovine Fetus

In Vivo Real-Time Study of Drug Effects on Carotid Blood Flow in the Ovine Fetus

205 Views

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11:59 min

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April 28, 2023

DOI:

10.3791/64551-v

DOI:
10.3791/64551-v

•

11:59 min
April 28, 2023

•

4 Views
, ,
1School of Animal and Comparative Biomedical Sciences, College of Agriculture and Life Sciences,University of Arizona, Tucson

Özet

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The present protocol describes a method to deliver drugs and gene expression-modifying agents perivascularly in an in utero developing fetus. Importantly, the effect of drugs/agents on blood flow can be measured with the progression of pregnancy.

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Pendleton, A. L., Limesand, S. W., Goyal, R. In Vivo Real-Time Study of Drug Effects on Carotid Blood Flow in the Ovine Fetus. J. Vis. Exp. (194), e64551, doi:10.3791/64551 (2023).

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