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In Vivo Real-Time Study of Drug Effects on Carotid Blood Flow in the Ovine Fetus
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In Vivo Real-Time Study of Drug Effects on Carotid Blood Flow in the Ovine Fetus
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April 28, 2023
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The present protocol describes a method to deliver drugs and gene expression-modifying agents perivascularly in an in utero developing fetus. Importantly, the effect of drugs/agents on blood flow can be measured with the progression of pregnancy.
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Pendleton, A. L., Limesand, S. W., Goyal, R. In Vivo Real-Time Study of Drug Effects on Carotid Blood Flow in the Ovine Fetus. J. Vis. Exp. (194), e64551, doi:10.3791/64551 (2023).
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