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Positron Emission Tomography Imaging for In Vivo Measuring of Myelin Content in the Lysolecithin Rat Model of Multiple Sclerosis
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JoVE Journal Nörobilim
Positron Emission Tomography Imaging for In Vivo Measuring of Myelin Content in the Lysolecithin Rat Model of Multiple Sclerosis

Positron Emission Tomography Imaging for In Vivo Measuring of Myelin Content in the Lysolecithin Rat Model of Multiple Sclerosis

DOI:
10.3791/62094-v

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08:40 min

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February 28, 2021

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, , , , ,
1Laboratory of Nuclear Medicine (LIM-43), Departamento de Radiologia e Oncologia, Faculdade de Medicina,Universidade de Sao Paulo, 2Nuclear Medicine Division,Hospital Sirio-Libanes

Bölümler

  • 00:00Introduction
  • 00:33Lysolecithin Solution Preparation
  • 01:10Lysolecithin Rat Model Stereotaxic Surgery
  • 03:01PET Acquisition
  • 04:47Image Analysis
  • 07:41Representative Results
  • 07:53Conclusion

Özet

Otomatik Çeviri

Otomatik Çeviri

This protocol has the aim of monitoring in vivo myelin changes (demyelination and remyelination) by positron emission tomography (PET) imaging in an animal model of multiple sclerosis.

Etiketler

Positron Emission TomographyPET ImagingMyelinLysolecithinMultiple SclerosisRat ModelStereotactic InjectionPIB TracerPET ScanIn Vivo ImagingTracer Injection

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