Positron Emission Tomography Imaging for <em>In Vivo</em> Measuring of Myelin Content in the Lysolecithin Rat Model of Multiple Sclerosis

Daniele de Paula Faria; Caroline Cristiano Real; Larissa Estessi de Souza; Alexandre Teles Garcez; Fabio Luis Navarro Marques; Carlos Alberto Buchpiguel

doi:10.3791/62094

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Positron Emission Tomography Imaging for In Vivo Measuring of Myelin Content in the Lysolecithin Rat Model of Multiple Sclerosis

JoVE Journal
Neuroscienze
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JoVE Journal Neuroscienze

Positron Emission Tomography Imaging for In Vivo Measuring of Myelin Content in the Lysolecithin Rat Model of Multiple Sclerosis

Positron Emission Tomography Imaging for In Vivo Measuring of Myelin Content in the Lysolecithin Rat Model of Multiple Sclerosis

3,939 Views

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08:40 min

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February 28, 2021

DOI:

10.3791/62094-v

DOI:

10.3791/62094-v

•

08:40 min

February 28, 2021

•

6 Views

Daniele de Paula Faria¹, Caroline Cristiano Real¹, Larissa Estessi de Souza¹, Alexandre Teles Garcez², Fabio Luis Navarro Marques¹, Carlos Alberto Buchpiguel¹

¹Laboratory of Nuclear Medicine (LIM-43), Departamento de Radiologia e Oncologia, Faculdade de Medicina,Universidade de Sao Paulo, ²Nuclear Medicine Division,Hospital Sirio-Libanes

Summary

This protocol has the aim of monitoring in vivo myelin changes (demyelination and remyelination) by positron emission tomography (PET) imaging in an animal model of multiple sclerosis.

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Positron Emission Tomography Imaging for In Vivo Measuring of Myelin Content in the Lysolecithin Rat Model of Multiple Sclerosis

Summary

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