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JoVE Journal Neuroscience
Positron Emission Tomography Imaging for In Vivo Measuring of Myelin Content in the Lysolecithin Rat Model of Multiple Sclerosis
 

Positron Emission Tomography Imaging for In Vivo Measuring of Myelin Content in the Lysolecithin Rat Model of Multiple Sclerosis

Article DOI: 10.3791/62094-v • 08:40 min • February 28th, 2021
February 28th, 2021 •
1, 1, 1, 2, 1, 1
1Laboratory of Nuclear Medicine (LIM-43), Departamento de Radiologia e Oncologia, Faculdade de Medicina, Universidade de Sao Paulo, 2Nuclear Medicine Division, Hospital Sirio-Libanes

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This protocol has the aim of monitoring in vivo myelin changes (demyelination and remyelination) by positron emission tomography (PET) imaging in an animal model of multiple sclerosis.

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Positron Emission Tomography PET Imaging In Vivo Measuring Myelin Content Lysolecithin Rat Model Multiple Sclerosis Monitoring PIB Labeling Carbonyl Imaging Technique In Vivo Images Mining Chains Stereotactic Injection Animal Model Induction Acquiring And Analyzing PIP Images Lysolecithin Solution Preparation Electronic Balance Glass Tube Plastic Tube Surgery Preparation Eye Cream 5% Codogen Solution Incision Area Cleaning Lidocaine Injection Hair Shaving Skull Incision Udak Clamps Bregma Positioning
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