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Cigarette Smoke Exposure in Mice using a Whole-Body Inhalation System
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Cigarette Smoke Exposure in Mice using a Whole-Body Inhalation System
1Program in Immunology,Baylor Tıp Fakültesi, 2Department of Pediatrics, Section of Infectious Diseases,Baylor Tıp Fakültesi, 3Department of Medicine – Immunology Allergy and Rheumatology,Baylor Tıp Fakültesi, 4Department of Medicine, Pulmonary, Critical Care, Sleep Medicine,Baylor Tıp Fakültesi, 5Department of Pathology and Immunology,Baylor Tıp Fakültesi, 6Department of Pediatrics, Research and Department of Epigenetics and Molecular Carcinogenesis,The University of Texas MD Anderson Cancer Center, 7Division of Pulmonary and Critical Care Medicine,The First Affiliated Hospital of Sun Yat-sen University, 8Center for Translational Research on Inflammatory Diseases (CTRID),Michael E. DeBakey VA Medical Center
Bölümler
- 00:04Introduction
- 00:34Setting Pressure and Airflow
- 01:46Cigarette Smoke Treatment
- 03:37Results: CS-mediated lnduction of Airway lnflammation and Lung Emphysematous Changes in Mice
- 05:14Conclusion
This protocol demonstrates the study of the pathophysiologic effects of cigarette smoke (CS) with a whole-body inhalation (WBI) exposure system (WBIS) built in-house. This system can expose animals to CS under controlled repeatable conditions for research of CS-mediated effects on lung emphysema and hematopoiesis.
