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Induction of Complete Transection-Type Spinal Cord Injury in Mice
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JoVE Journal Nörobilim
Induction of Complete Transection-Type Spinal Cord Injury in Mice

Induction of Complete Transection-Type Spinal Cord Injury in Mice

7,567 Views

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06:51 min

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May 06, 2020

DOI:

10.3791/61131-v

DOI:
10.3791/61131-v

•

06:51 min
May 06, 2020

•

8 Views
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1Griffith Institute for Drug Discovery,Griffith University, 2Menzies Health Institute Queensland,Griffith University, 3Clem Jones Centre for Neurobiology and Stem Cell Research,Griffith University

Özet

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This protocol describes how to create a precise laminectomy for induction of stable transection-type spinal cord injury in the mouse model, with minimal collateral damage for spinal cord injury research.

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Spinal Cord InjuryTransectionLaminectomyMouse ModelVertebraeLaminaeDrillDissectionForcepsSurgical Procedure

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Cite this Article

Reshamwala, R., Eindorf, T., Shah, M., Smyth, G., Shelper, T., St. John, J., Ekberg, J. Induction of Complete Transection-Type Spinal Cord Injury in Mice. J. Vis. Exp. (159), e61131, doi:10.3791/61131 (2020).

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