Induction of Complete Transection-Type Spinal Cord Injury in Mice

Ronak Reshamwala; Tanja Eindorf; Megha Shah; Graham Smyth; Todd Shelper; James St. John; Jenny Ekberg

doi:10.3791/61131

Journal

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Neurosciences

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Induction of Complete Transection-Type Spinal Cord Injury in Mice

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Neurosciences

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Journal JoVE Neurosciences

Induction of Complete Transection-Type Spinal Cord Injury in Mice

7,505 Views

•

06:51 min

•

May 06, 2020

DOI:

10.3791/61131-v

DOI:

10.3791/61131-v

•

06:51 min

May 06, 2020

•

8 Views

Ronak Reshamwala^1,2,3, Tanja Eindorf^2,3, Megha Shah^2,3, Graham Smyth^2,3, Todd Shelper^2,3, James St. John*^1,2,3, Jenny Ekberg*^2,3

¹Griffith Institute for Drug Discovery,Griffith University, ²Menzies Health Institute Queensland,Griffith University, ³Clem Jones Centre for Neurobiology and Stem Cell Research,Griffith University

Summary

This protocol describes how to create a precise laminectomy for induction of stable transection-type spinal cord injury in the mouse model, with minimal collateral damage for spinal cord injury research.

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Induction of Complete Transection-Type Spinal Cord Injury in Mice

Summary

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