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Induction of Complete Transection-Type Spinal Cord Injury in Mice
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Journal JoVE Neurosciences
Induction of Complete Transection-Type Spinal Cord Injury in Mice

Induction of Complete Transection-Type Spinal Cord Injury in Mice

DOI:
10.3791/61131-v

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06:51 min

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May 06, 2020

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, , , , , ,
1Griffith Institute for Drug Discovery,Griffith University, 2Menzies Health Institute Queensland,Griffith University, 3Clem Jones Centre for Neurobiology and Stem Cell Research,Griffith University

Chapitres

  • 00:04Introduction
  • 00:37Laminectomy
  • 03:39Transection and Closure
  • 04:54Results: Representative Transection Type Injury Results
  • 06:13Conclusion

Summary

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This protocol describes how to create a precise laminectomy for induction of stable transection-type spinal cord injury in the mouse model, with minimal collateral damage for spinal cord injury research.

Tags

Keywords: Spinal Cord InjuryTransectionLaminectomyMouse ModelVertebraeLaminaeDrillDissectionForcepsSurgical Procedure

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