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Caracterización de estructuras amiloideas en el envejecimiento C. Elegans usando imágenes de por vida de fluorescencia
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JoVE Journal Biyokimya
Characterization of Amyloid Structures in Aging C. Elegans Using Fluorescence Lifetime Imaging
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Caracterización de estructuras amiloideas en el envejecimiento C. Elegans usando imágenes de por vida de fluorescencia

6,780 Views

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09:31 min

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March 27, 2020

DOI:

10.3791/61004-v

DOI:
10.3791/61004-v

•

09:31 min
March 27, 2020

•

3 Views
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1Leibniz Research Institute for Molecular Pharmacology im Forschungsverbund Berlin, 2NeuroCure Cluster of Excellence,Charité – Universitätsmedizin Berlin, 3Molecular Neuroscience Group, Department of Chemical Engineering and Biotechnology,University of Cambridge, 4Cell Biology,University of Bremen

Özet

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La fluorescencia de por vida de los monitores de imágenes, cuantifica y distingue las tendencias de agregación de las proteínas en los modelos de enfermedad de C. elegans, vivos, envejecidos y estresados.

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Pigazzini, M. L., Gallrein, C., Iburg, M., Kaminski Schierle, G., Kirstein, J. Characterization of Amyloid Structures in Aging C. Elegans Using Fluorescence Lifetime Imaging. J. Vis. Exp. (157), e61004, doi:10.3791/61004 (2020).

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