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Characterization of Amyloid Structures in Aging C. Elegans Using Fluorescence Lifetime Imaging
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Bioquímica
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JoVE Journal Bioquímica
Characterization of Amyloid Structures in Aging C. Elegans Using Fluorescence Lifetime Imaging

Characterization of Amyloid Structures in Aging C. Elegans Using Fluorescence Lifetime Imaging

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09:31 min

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March 27, 2020

DOI:

10.3791/61004-v

DOI:
10.3791/61004-v

•

09:31 min
March 27, 2020

•

3 Views
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1Leibniz Research Institute for Molecular Pharmacology im Forschungsverbund Berlin, 2NeuroCure Cluster of Excellence,Charité – Universitätsmedizin Berlin, 3Molecular Neuroscience Group, Department of Chemical Engineering and Biotechnology,University of Cambridge, 4Cell Biology,University of Bremen

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Fluorescence lifetime imaging monitors, quantifies and distinguishes the aggregation tendencies of proteins in living, aging, and stressed C. elegans disease models.

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Amyloid StructuresFluorescence Lifetime ImagingProtein AggregationC. ElegansNeurodegenerative DiseasesFLIMAgarose PadsNematodes

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Cite this Article

Pigazzini, M. L., Gallrein, C., Iburg, M., Kaminski Schierle, G., Kirstein, J. Characterization of Amyloid Structures in Aging C. Elegans Using Fluorescence Lifetime Imaging. J. Vis. Exp. (157), e61004, doi:10.3791/61004 (2020).

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