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Characterization of Amyloid Structures in Aging C. Elegans Using Fluorescence Lifetime Imaging
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Biochimie
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Journal JoVE Biochimie
Characterization of Amyloid Structures in Aging C. Elegans Using Fluorescence Lifetime Imaging

Characterization of Amyloid Structures in Aging C. Elegans Using Fluorescence Lifetime Imaging

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09:31 min

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March 27, 2020

DOI:

10.3791/61004-v

DOI:
10.3791/61004-v

•

09:31 min
March 27, 2020

•

3 Views
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1Leibniz Research Institute for Molecular Pharmacology im Forschungsverbund Berlin, 2NeuroCure Cluster of Excellence,Charité – Universitätsmedizin Berlin, 3Molecular Neuroscience Group, Department of Chemical Engineering and Biotechnology,University of Cambridge, 4Cell Biology,University of Bremen

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Fluorescence lifetime imaging monitors, quantifies and distinguishes the aggregation tendencies of proteins in living, aging, and stressed C. elegans disease models.

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Amyloid StructuresFluorescence Lifetime ImagingProtein AggregationC. ElegansNeurodegenerative DiseasesFLIMAgarose PadsNematodes

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Pigazzini, M. L., Gallrein, C., Iburg, M., Kaminski Schierle, G., Kirstein, J. Characterization of Amyloid Structures in Aging C. Elegans Using Fluorescence Lifetime Imaging. J. Vis. Exp. (157), e61004, doi:10.3791/61004 (2020).

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