Delivery of Modified mRNA in a Myocardial Infarction Mouse Model

Keerat Kaur; Nishat Sultana; Yoav Hadas; Ajit Magadum; Mohammad Tofael Kabir Sharkar; Elena Chepurko; Lior Zangi

doi:10.3791/60832

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Genetik

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Entrega de ARNm modificado en un modelo de ratón de infarto de miocardio

JoVE Journal
Genetik

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JoVE Journal Genetik

Delivery of Modified mRNA in a Myocardial Infarction Mouse Model

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Entrega de ARNm modificado en un modelo de ratón de infarto de miocardio

8,695 Views

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06:03 min

•

June 11, 2020

DOI:

10.3791/60832-v

DOI:

10.3791/60832-v

•

06:03 min

June 11, 2020

•

26 Views

Keerat Kaur^1,2,3, Nishat Sultana^1,2,3, Yoav Hadas^1,2,3, Ajit Magadum^1,2,3, Mohammad Tofael Kabir Sharkar^1,2,3, Elena Chepurko^1,2,3, Lior Zangi^1,2,3

¹Cardiovascular Research Center,Icahn School of Medicine at Mount Sinai, ²Department of Genetics and Genomic Sciences,Icahn School of Medicine at Mount Sinai, ³Black Family Stem Cell Institute,Icahn School of Medicine at Mount Sinai

Özet

Este protocolo presenta una manera simple y coherente de regular transitoriamente un gen de interés utilizando modRNA después del infarto de miocardio en ratones.

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Entrega de ARNm modificado en un modelo de ratón de infarto de miocardio

Özet

Automatically generated

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