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在重复性扩散创伤性脑损伤小鼠模型中诱导创伤后癫痫
JoVE Journal
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JoVE Journal Davranış
Inducing Post-Traumatic Epilepsy in a Mouse Model of Repetitive Diffuse Traumatic Brain Injury
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在重复性扩散创伤性脑损伤小鼠模型中诱导创伤后癫痫

DOI:
10.3791/60360-v

•

07:07 min

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February 10, 2020

•

,
1Fralin Biomedical Research Institute at Virginia Tech Carilion, 2School of Neuroscience,Virginia Tech, 3Department of Biological Sciences,Virginia Tech

Bölümler

  • 00:04Başlık
  • 00:56Weight Drop Traumatic Brain Injury (TBI)
  • 02:01Electroencephalography (EEG) Electrode Implantation Surgical Field Preparation
  • 03:11EEG Electrode Implantation
  • 05:13Results: Representative Spontaneous Seizure Depictions and Timelines
  • 06:17Conclusion

Özet

Otomatik Çeviri

Otomatik Çeviri

此系统协议描述了重复性轻度创伤性脑损伤后创伤后癫痫的新动物模型。第一部分详细介绍了使用修改后的降重模型进行创伤性脑损伤诱导的步骤。第二部分对单通道和多通道脑电图数据采集系统的手术方法进行了说明。

Etiketler

Post-traumatic EpilepsyMouse ModelTraumatic Brain InjuryDiffuse InjuryBiomarkersTreatmentsMild Traumatic Brain InjuryConcussionEEG Electrode ImplantationStereotactic ApparatusPeriosteumCraniumHigh-speed Drill

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