Flash NanoPrecipitation for the Encapsulation of Hydrophobic and Hydrophilic Compounds in Polymeric Nanoparticles

Chester E. Markwalter; Robert F. Pagels; Brian K. Wilson; Kurt D. Ristroph; Robert K. Prud'homme

doi:10.3791/58757

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Flash NanoPrecipitation for the Encapsulation of Hydrophobic and Hydrophilic Compounds in Polymeric Nanoparticles

JoVE Journal
Biyomühendislik

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JoVE Journal Biyomühendislik

Flash NanoPrecipitation for the Encapsulation of Hydrophobic and Hydrophilic Compounds in Polymeric Nanoparticles

20,893 Views

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10:12 min

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January 07, 2019

DOI:

10.3791/58757-v

DOI:

10.3791/58757-v

•

10:12 min

January 07, 2019

•

32 Views

Chester E. Markwalter*, Robert F. Pagels*, Brian K. Wilson*, Kurt D. Ristroph*, Robert K. Prud’homme*

¹Department of Chemical and Biological Engineering,Princeton University

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Flash NanoPrecipitation (FNP) is a scalable approach to produce polymeric core-shell nanoparticles. Lab-scale formulations for the encapsulation of hydrophobic or hydrophilic therapeutics are described.

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Flash NanoPrecipitation for the Encapsulation of Hydrophobic and Hydrophilic Compounds in Polymeric Nanoparticles

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