Bu içeriği görüntülemek için JoVE aboneliği gereklidir. Oturum açın veya ücretsiz deneme sürümünü başlatın.
Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers
7,731 Views
•
08:28 min
•
September 19, 2017
DOI:
1School of Pharmacy, Tongji Medical College,Huazhong University of Science and Technology, 2Mechanobiology Institute,National University of Singapore, 3Fizik Bölümü,National University of Singapore, 4Research Institute for Biomimetics and Soft Matter, Fujian Provincial Key Lab for Soft Functional Materials Research, Department of Physics,Xiamen University, 5Center for Bioimaging Sciences,National University of Singapore
Özet
Automatically generated
A single-molecule magnetic tweezers platform to manipulate G-quadruplexes is reported, which allows for the study of G4 stability and regulation by various proteins.
Read Article
Cite this Article
You, H., Le, S., Chen, H., Qin, L., Yan, J. Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers. J. Vis. Exp. (127), e56328, doi:10.3791/56328 (2017).
Copy