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Shifting Zebrafish Lethal Skeletal Mutant Penetrance by Progeny Testing
JoVE Journal
Gelişim Biyolojisi
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JoVE Journal Gelişim Biyolojisi
Shifting Zebrafish Lethal Skeletal Mutant Penetrance by Progeny Testing

Shifting Zebrafish Lethal Skeletal Mutant Penetrance by Progeny Testing

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08:39 min

September 01, 2017

DOI:

08:39 min
September 01, 2017

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Özet

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The goal of this protocol is to alter the penetrance of lethal skeletal mutant phenotypes in zebrafish by selective breeding. Lethal mutants cannot be grown to adulthood and bred themselves, therefore this protocol describes a method for tracking and selecting penetrance through multiple generations by progeny testing.

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