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Determining the Optimal Inhibitory Frequency for Cancerous Cells Using Tumor Treating Fields (TTFields)
JoVE Journal
Kanser Araştırmaları
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JoVE Journal Kanser Araştırmaları
Determining the Optimal Inhibitory Frequency for Cancerous Cells Using Tumor Treating Fields (TTFields)

Determining the Optimal Inhibitory Frequency for Cancerous Cells Using Tumor Treating Fields (TTFields)

DOI:
10.3791/55820-v

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08:14 min

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May 04, 2017

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, , , , , , , , , , , ,
1Preclinical Research Department,Novocure Ltd., Haifa, Israel, 2Novocure Ltd., Haifa, Israel, 3Novocure GmbH, Lucerne, Switzerland

Bölümler

  • 00:05Başlık
  • 01:00Experimental Setup
  • 02:32TTFields Application
  • 05:17Evaluation of TTFields Effect
  • 06:04Results: Frequency-dependent Growth Inhibitory Effect of TTFields
  • 06:58Conclusion

Özet

Otomatik Çeviri

Otomatik Çeviri

Tumor Treating Fields (TTFields) are an effective anti-tumor treatment modality delivered via the continuous, noninvasive application of low-intensity, intermediate-frequency, alternating electric fields. TTFields application to cell lines using a TTFields in vitro application system allows for the determination of the optimal frequency that leads to the highest reduction in cell counts.

Etiketler

Tumor Treating Fields (TTFields)In VitroCancer CellsInhibitory FrequencyCell Growth InhibitionU-87 MG CellsDMEM MediumCell SuspensionCoverslipGrowth MediumRefrigerated IncubatorElectric Field IntensityTTFields GeneratorPre-clinical IdentificationCombined TreatmentChemotherapyRadiation Therapy

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