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Determining the Optimal Inhibitory Frequency for Cancerous Cells Using Tumor Treating Fields (TTFields)
JoVE Journal
Krebsforschung
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JoVE Journal Krebsforschung
Determining the Optimal Inhibitory Frequency for Cancerous Cells Using Tumor Treating Fields (TTFields)

Determining the Optimal Inhibitory Frequency for Cancerous Cells Using Tumor Treating Fields (TTFields)

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08:14 min

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May 04, 2017

DOI:

10.3791/55820-v

DOI:
10.3791/55820-v

•

08:14 min
May 04, 2017

•

29 Views
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1Preclinical Research Department,Novocure Ltd., Haifa, Israel, 2Novocure Ltd., Haifa, Israel, 3Novocure GmbH, Lucerne, Switzerland

Summary

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Tumor Treating Fields (TTFields) are an effective anti-tumor treatment modality delivered via the continuous, noninvasive application of low-intensity, intermediate-frequency, alternating electric fields. TTFields application to cell lines using a TTFields in vitro application system allows for the determination of the optimal frequency that leads to the highest reduction in cell counts.

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Porat, Y., Giladi, M., Schneiderman, R. S., Blat, R., Shteingauz, A., Zeevi, E., Munster, M., Voloshin, T., Kaynan, N., Tal, O., Kirson, E. D., Weinberg, U., Palti, Y. Determining the Optimal Inhibitory Frequency for Cancerous Cells Using Tumor Treating Fields (TTFields). J. Vis. Exp. (123), e55820, doi:10.3791/55820 (2017).

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