Bu içeriği görüntülemek için JoVE aboneliği gereklidir. Oturum açın veya ücretsiz deneme sürümünü başlatın.
Atomic Force Microscopy Investigations of DNA Lesion Recognition in Nucleotide Excision Repair
9,246 Views
•
10:59 min
•
May 24, 2017
DOI:
Özet
Automatically generated
Here, the study of different DNA lesion recognition approaches via single molecule AFM imaging is demonstrated with the nucleotide excision repair system as an example. The procedures of DNA and protein sample preparations and experimental as well as analytical details for the AFM experiments are described.
Read Article
Cite this Article
Gross, J., Wirth, N., Tessmer, I. Atomic Force Microscopy Investigations of DNA Lesion Recognition in Nucleotide Excision Repair. J. Vis. Exp. (123), e55501, doi:10.3791/55501 (2017).
Copy