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Atomic Force Microscopy Investigations of DNA Lesion Recognition in Nucleotide Excision Repair
JoVE Journal
Genetica
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JoVE Journal Genetica
Atomic Force Microscopy Investigations of DNA Lesion Recognition in Nucleotide Excision Repair

Atomic Force Microscopy Investigations of DNA Lesion Recognition in Nucleotide Excision Repair

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10:59 min

May 24, 2017

DOI:

10:59 min
May 24, 2017

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Summary

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Here, the study of different DNA lesion recognition approaches via single molecule AFM imaging is demonstrated with the nucleotide excision repair system as an example. The procedures of DNA and protein sample preparations and experimental as well as analytical details for the AFM experiments are described.

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