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Triggering Cell Stress and Death Using Conventional UV Laser Confocal Microscopy
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February 03, 2017
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Targeted manipulations to cause directed stress or death in individual cells have been relatively difficult to accomplish. Here, a single-cell-resolution ablation approach to selectively stress and kill individual cells in cell culture and living animals is described based on a standard confocal UV laser.
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Morsch, M., Radford, R. A. W., Don, E. K., Lee, A., Hortle, E., Cole, N. J., Chung, R. S. Triggering Cell Stress and Death Using Conventional UV Laser Confocal Microscopy. J. Vis. Exp. (120), e54983, doi:10.3791/54983 (2017).
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