Dergi
/
Nörobilim
/
Mikroglia als Surrogate Biosensor Nanoparticle Neurotoxicity zu ermitteln
JoVE Journal
Nörobilim
Bu içeriği görüntülemek için JoVE aboneliği gereklidir.  Oturum açın veya ücretsiz deneme sürümünü başlatın.
JoVE Journal Nörobilim
Microglia as a Surrogate Biosensor to Determine Nanoparticle Neurotoxicity
Please note that all translations are automatically generated. Click here for the English version.

Mikroglia als Surrogate Biosensor Nanoparticle Neurotoxicity zu ermitteln

6,836 Views

•

08:37 min

•

October 25, 2016

DOI:

10.3791/54662-v

DOI:
10.3791/54662-v

•

08:37 min
October 25, 2016

•

1 Views
, , , , ,
1Minneapolis Veterans Affairs Health Care System, 2Department of Food Science and Nutrition,University of Minnesota, 3Biomedical Informatics and Computational Biology Program,University of Minnesota, 4Minnesota Obesity Center,University of Minnesota

Özet

Automatically generated

Microglia (immune cells of the brain), are used as a surrogate biosensor to determine how nanoparticles influence neurotoxicity. We describe a series of experiments designed to assay microglial response to nanoparticles and exposure of hypothalamic neurons to supernatant from activated microglia to determine neurotoxicity.

Explore More Videos

MicrogliaBiosensorNanoparticleNeurotoxicityNörobilimIn VitroCell CultureBV2 CellsSilver NanoparticlesConditioned MediaFiltrationCell CountingCell SeedingCell StarvationCell Activation

Read Article

Cite this Article

Duffy, C. M., Ahmed, S., Yuan, C., Mavanji, V., Nixon, J. P., Butterick, T. Microglia as a Surrogate Biosensor to Determine Nanoparticle Neurotoxicity. J. Vis. Exp. (116), e54662, doi:10.3791/54662 (2016).

Download .ris file

Copy

Share Video

.

Copy