Dergi
/
Tıp
/
Diffuse Optical Spectroscopy for the Quantitative Assessment of Acute Ionizing Radiation Induced Skin Toxicity Using a Mouse Model
JoVE Journal
Tıp
This content is Free Access.
JoVE Journal Tıp
Diffuse Optical Spectroscopy for the Quantitative Assessment of Acute Ionizing Radiation Induced Skin Toxicity Using a Mouse Model

Diffuse Optical Spectroscopy for the Quantitative Assessment of Acute Ionizing Radiation Induced Skin Toxicity Using a Mouse Model

7,866 Views

•

06:21 min

•

May 27, 2016

DOI:

10.3791/53573-v

DOI:
10.3791/53573-v

•

06:21 min
May 27, 2016

•

3 Views
, , , , , ,
1Radyasyon Onkoloji Bölümü,University of Toronto, 2Fizik Bölümü,Ryerson University, 3Department of Medical Biophysics,University of Toronto, 4Ontario Cancer Institute / Campbell Family Institute for Cancer Research

Özet

Automatically generated

We present a diffuse optical spectroscopic (DOS) approach that provides quantitative optical biomarkers of skin response to radiation. We describe DOS instrumentation design, optical parameters extraction algorithms and the animal handling procedures required to yield representative data from a pre-clinical mouse model of radiation induced erythema.

Explore More Videos

Diffuse Optical SpectroscopyAcute Ionizing RadiationSkin ToxicityMouse ModelBiomarkerRadiation TherapyRadiation Skin ToxicityReflectanceAnesthesiaMouse Irradiation

Read Article

Cite this Article

Chin, L., Korpela, E., Kim, A., Yohan, D., Niu, C., Wilson, B. C., Liu, S. K. Diffuse Optical Spectroscopy for the Quantitative Assessment of Acute Ionizing Radiation Induced Skin Toxicity Using a Mouse Model. J. Vis. Exp. (111), e53573, doi:10.3791/53573 (2016).

Download .ris file

Copy

Share Video

.

Copy