Classical forelimb asymmetry analysis of the cylinder test is routinely used to assess behavioural deficits in rats following brain injury or stroke; however, it fails to detect consistent deficits in mice. This study demonstrates that quantifying paw-dragging behaviour is a more sensitive analysis of brain injury in mice.
Roome, R. B., Vanderluit, J. L. Paw-Dragging: a Novel, Sensitive Analysis of the Mouse Cylinder Test. J. Vis. Exp. (98), e52701, doi:10.3791/52701 (2015).