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Paw-Dragging: a Novel, Sensitive Analysis of the Mouse Cylinder Test
章
- 00:00標題
- 00:14Introduction
- 03:07Set-up of the Mouse Cylinder Test
- 04:32Conducting the Mouse Cylinder Test
- 05:07Analysis of the Mouse Cylinder Test
- 05:54Quantifying Paw Dragging Behavior
- 06:59Identifying Behavior that is not a Paw Drag
- 07:53Representative Results
- 08:31Conclusion
Classical forelimb asymmetry analysis of the cylinder test is routinely used to assess behavioural deficits in rats following brain injury or stroke; however, it fails to detect consistent deficits in mice. This study demonstrates that quantifying paw-dragging behaviour is a more sensitive analysis of brain injury in mice.
