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Three-Dimensional (3D) Tumor Spheroid Invasion Assay
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Three-Dimensional (3D) Tumor Spheroid Invasion Assay

Three-Dimensional (3D) Tumor Spheroid Invasion Assay

55,557 Views

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12:19 min

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May 01, 2015

DOI:

10.3791/52686-v

DOI:
10.3791/52686-v

•

12:19 min
May 01, 2015

•

38 Views
, ,
1Division of Molecular Pathology,The Institute of Cancer Research, 2Division of Cancer Therapeutics,The Institute of Cancer Research

Özet

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Invasion of surrounding normal tissues is a defining characteristic of malignant tumors. We provide here a simple, semi-automated micro-plate assay of invasion into a natural 3D biomatrix that has been exemplified with a number of models of advanced human cancers.

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Cite this Article

Vinci, M., Box, C., Eccles, S. A. Three-Dimensional (3D) Tumor Spheroid Invasion Assay. J. Vis. Exp. (99), e52686, doi:10.3791/52686 (2015).

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