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The Sciatic Nerve Cuffing Model of Neuropathic Pain in Mice
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The Sciatic Nerve Cuffing Model of Neuropathic Pain in Mice

The Sciatic Nerve Cuffing Model of Neuropathic Pain in Mice

DOI:
10.3791/51608-v

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07:09 min

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July 16, 2014

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, , , , , ,
1Institut des Neurosciences Cellulaires et Intégratives UPR3212,Centre National de la Recherche Scientifique, 2Université de Strasbourg, 3Hôpitaux Universitaires de Strasbourg

Bölümler

  • 00:05Başlık
  • 01:27Measuring Paw Withdrawal: Von Frey Test
  • 03:20Cuff Implantation Surgery
  • 05:51Drug Treatments and Pain Responses
  • 06:37Conclusion

Özet

Otomatik Çeviri

Otomatik Çeviri

Neuropathic pain is a consequence of a lesion or disease affecting the somatosensory system. The “cuff model” of neuropathic pain in mice consists of the implantation of a polyethylene cuff around the main branch of the sciatic nerve. Mechanical allodynia is tested using von Frey filaments.

Etiketler

Sciatic NerveNeuropathic PainMurine ModelPeripheral Nerve InjuryCuff ModelMechanical AllodyniaVon Frey FilamentsSomatosensory SystemNociceptive PathwayCentral Nervous SystemChronic PainTreatment

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