Bu içeriği görüntülemek için JoVE aboneliği gereklidir. Oturum açın veya ücretsiz deneme sürümünü başlatın.
Un protocole double Tracer TEP-IRM pour la mesure quantitative de la régionale cerveau substrats énergétiques absorption chez le rat
1Research Center on Aging and Department of Physiology and Biophysics,Sherbrooke Üniversitesi, 2Sherbrooke Molecular Imaging Center, Étienne-Le Bel Clinical Research Center,Sherbrooke Üniversitesi, 3Department of Computer Science,Sherbrooke Üniversitesi, 4Department of Nuclear Medicine and Radiobiology,Sherbrooke Üniversitesi
Bölümler
- 00:05Başlık
- 02:19Brain Anatomy with MRI
- 03:19Dual Tracer PET Acquisitions
- 08:29Quantitative PET Analysis
- 12:56Results: Dual Tracer PET-MRI
- 14:00Conclusion
Small-animal positron emission tomography enables the assessment of the brain's two main energy substrates: glucose and ketones. In the present method, 11C-acetoacetate and 18F-fluorodeoxyglucose are injected sequentially in each animal, and their uptake is measured quantitatively in specific brain regions determined from the magnetic resonance images.
