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Hippocampus Insulin Mikroinjektion und<em> In vivo</em> Microdialysis Während Spatial Memory Testing
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January 11, 2013
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Modulation der hippocampally-abhängige räumliche Arbeitsgedächtnis durch direkte intrahippocampal Mikroinjektion, begleitet und gefolgt von<em> In vivo</em> Mikrodialyse für Metaboliten in der bewussten, sich verhaltenden Tier.
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Hippocampal Insulin MicroinjectionIn Vivo MicrodialysisSpatial Memory TestingGlucose MetabolismNeural Activity Marker2-deoxyglucoseFunctional Magnetic Resonance ImagingAnesthesiaBehavioral MeasuresBrain State AlterationContinuous MeasurementBrain Extracellular Fluid ConcentrationsLactateMetabolitesAwake AnimalsUnrestrained AnimalsTasks Designed For Specific Brain RegionsAcute Pharmacological ManipulationHippocampal MeasurementsSpatial Working Memory TaskSpontaneous AlternationEnhanced GlycolysisIntrahippocampal Insulin AdministrationMemory ImprovementHippocampal GlycolysisMicrodialysis Probe DeliveryMetabolite MeasurementSpontaneous Alternation TaskHippocampal Function Measure
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McNay, E. C., Sandusky, L. A., Pearson-Leary, J. Hippocampal Insulin Microinjection and In vivo Microdialysis During Spatial Memory Testing. J. Vis. Exp. (71), e4451, doi:10.3791/4451 (2013).
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