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08:50 min
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May 12, 2023
DOI:
1Department of Physics,Pohang University of Science and Technology (POSTECH), 2School of Biological Sciences,Seoul National University, 3Institute for Molecular Biology and Genetics,Seoul National University, 4School of Interdisciplinary Bioscience and Bioengineering,Pohang University of Science and Technology (POSTECH)
Summary
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在这里，我们描述了一种高速磁镊装置，该装置以最大1.2 kHz的速率对力敏生物分子进行纳米力学测量。我们将它作为模型系统介绍其在DNA发夹和SNARE复合物中的应用，但它也适用于参与机械生物学事件的其他分子。
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Cite this Article
Park, C., Yang, T., Rah, S., Kim, H. G., Yoon, T., Shon, M. J. High-Speed Magnetic Tweezers for Nanomechanical Measurements on Force-Sensitive Elements. J. Vis. Exp. (195), e65137, doi:10.3791/65137 (2023).
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