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High-Speed Magnetic Tweezers for Nanomechanical Measurements on Force-Sensitive Elements
JoVE 杂志
生物化学
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JoVE 杂志 生物化学
High-Speed Magnetic Tweezers for Nanomechanical Measurements on Force-Sensitive Elements

High-Speed Magnetic Tweezers for Nanomechanical Measurements on Force-Sensitive Elements

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08:50 min

May 12, 2023

DOI:

08:50 min
May 12, 2023

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Summary

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Here, we describe a high-speed magnetic tweezer setup that performs nanomechanical measurements on force-sensitive biomolecules at the maximum rate of 1.2 kHz. We introduce its application to DNA hairpins and SNARE complexes as model systems, but it will be also applicable to other molecules involved in mechanobiological events.

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