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Generating Genetically Modified Plasmodium berghei Sporozoites
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May 05, 2023
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Malaria is transmitted through inoculation of the sporozoite stage of Plasmodium by infected mosquitoes. Transgenic Plasmodium has allowed us to understand the biology of malaria better and has contributed directly to malaria vaccine development efforts. Here, we describe a streamlined methodology to generate transgenic Plasmodium berghei sporozoites.
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Bowers, C., Kurup, S. P. Generating Genetically Modified Plasmodium berghei Sporozoites. J. Vis. Exp. (195), e64992, doi:10.3791/64992 (2023).
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